Mitotic chromosome organization: General rules meet species-specific variability
نویسندگان
چکیده
منابع مشابه
Organization of the mitotic chromosome.
Mitotic chromosomes are among the most recognizable structures in the cell, yet for over a century their internal organization remains largely unsolved. We applied chromosome conformation capture methods, 5C and Hi-C, across the cell cycle and revealed two distinct three-dimensional folding states of the human genome. We show that the highly compartmentalized and cell type-specific organization...
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ژورنال
عنوان ژورنال: Computational and Structural Biotechnology Journal
سال: 2020
ISSN: 2001-0370
DOI: 10.1016/j.csbj.2020.01.006